A Retrospective Study on Assessment of Safety and Effectiveness of Antibiotics among Infectious Disease Patients in a Secondary Care Hospital

Aims: To assess the safety and effectiveness of the antibiotics among infectious disease patients.

Study Design: Retrospective study.

Place and Duration of Study: Palana Institute of Medical Sciences, Palakkad, between April 2024 to September 2024.

Methodology: A Retrospective study of 6-month duration was conducted in a secondary care hospital. The study included all the inpatients diagnosed with an infectious disease and received at least one antibiotic. The patient data collection form was designed in order to collect the patient demographic details and details of antibiotic therapy and the details of the culture sensitivity test using hospital software (HIMS). Data collection was performed and the collected data were analysed using descriptive statistics and MS Excel.

Results: A total of 74 patients were included in this study, among which 39 were male and 35 were female. Majority of the participants were among the age group of 60-75 years (29.73%). Out of 74, 33 patients were diagnosed with respiratory tract infections. 51.43% of study population were performed their culsture sensitivity test for both blood and urine samples. Penicillins and Cephalosporins were the most commonly prescribed antibiotics and the common adverse effects with these drugs were itching, rashes and redness. 14 (37.84%) of the study population were both sensitive and resistance to at least one antibiotic, 8 (21.62%) of the study population were Sensitive to all antibiotics.

Conclusion: Rational use of antibiotics plays an important role in controlling the unnecessary use of it and also prevents the development of antibiotic resistance and adverse drug reactions.